Amy Byers, PhD, MPH

Core Investigator
+1 415 221-4810 ext. 3980

Dr. Byers is an epidemiologist with a background in aging research, methods, and biostatistics. Her research focuses on the epidemiology of late-life mental health and employs advanced epidemiological and biostatistical techniques to determine the prevalence, risk factors, and outcomes of late-life mental health disorders with the objective of reducing the burden of these disorders by informing long-term clinical care. As a clinical epidemiologist studying geropsychiatry with an expertise in mathematical epidemiology, Dr. Byers has been heavily involved in research to determine nationally representative estimates of psychiatric disorders and health care utilization among older community-dwelling adults.

Dr. Byers was the recipient of an NIH K01 Career Development award that involved the application of advanced methodology to address complex clinical questions on the onset, course, and outcomes of geriatric depression. She was also the recipient of a Department of Defense grant that investigated late-life PTSD and adverse health outcomes such as morbidity, mortality, and health services utilization among US Veterans, the first comprehensive longitudinal examination of late-life PTSD and adverse health outcomes in this population. Recently, Dr. Byers has been awarded a Department of Veterans Affairs CSR&D Merit award to study suicide and suicidal behavior among older US Veterans. She has also received an NIH R01 award to study the prevalence and key predictors of suicide-related behaviors in ethnically-diverse older Americans and to examine mental health services use in older Americans at increased risk of suicide.

Dr. Byers has had her research published in many prestigious journals including the New England Journal of Medicine, Archives of Internal Medicine/JAMA Internal Medicine, and Archives of General Psychiatry/JAMA Psychiatry.

Publications: 

Gender Differences in Cardiovascular Risk Related to Diabetes and Posttraumatic Stress Disorder.

American Journal of Geriatric Psychiatry

Gibson CJ, Li Y, Inslicht SS, Seal KH, Byers AL

High Occurrence of Psychiatric Disorders and Suicidal Behavior Across Dementia Subtypes.

American Journal of Geriatric Psychiatry

Lai AX, Kaup AR, Yaffe K, Byers AL

Burden of Depressive Symptoms Over 2 Decades and Risk of Nursing Home Placement in Older Women.

Journal of the American Geriatrics Society

Byers AL, Lui LY, Vittinghoff E, Covinsky KE, Ensrud KE, Taylor B, Yaffe K

Increased Risk of Suicide Attempts and Unintended Death Among Those Transitioning From Prison to Community in Later Life.

American Journal of Geriatric Psychiatry

Barry LC, Steffens DC, Covinsky KE, Conwell Y, Li Y, Byers AL

Association of Mild Traumatic Brain Injury With and Without Loss of Consciousness With Dementia in US Military Veterans.

JAMA neurology

Barnes DE, Byers AL, Gardner RC, Seal KH, Boscardin WJ, Yaffe K

Mild TBI and risk of Parkinson disease: A Chronic Effects of Neurotrauma Consortium Study.

Neurology

Gardner RC, Byers AL, Barnes DE, Li Y, Boscardin J, Yaffe K

Traumatic Brain Injury and Receipt of Prescription Opioid Therapy for Chronic Pain in Iraq and Afghanistan Veterans: Do Clinical Practice Guidelines Matter?

The journal of pain : official journal of the American Pain Society

Seal KH, Bertenthal D, Barnes DE, Byers AL, Gibson CJ, Yaffe K

Predictors of Mental Health Services Use Across the Life Course among Racially-Ethnically Diverse Adults.

American Journal of Geriatric Psychiatry

Byers AL, Lai AX, Nelson C, Yaffe K

Association of Traumatic Brain Injury With Chronic Pain in Iraq and Afghanistan Veterans: Effect of Comorbid Mental Health Conditions.

Archives of physical medicine and rehabilitation

Seal KH, Bertenthal D, Barnes DE, Byers AL, Strigo I, Yaffe K

Trajectories of Depressive Symptoms in Older Adults and Risk of Dementia.

JAMA psychiatry

Kaup AR, Byers AL, Falvey C, Simonsick EM, Satterfield S, Ayonayon HN, Smagula SF, Rubin SM, Yaffe K

TRAUMA EXPOSURE AND RISK OF SUICIDAL IDEATION AMONG ETHNICALLY DIVERSE ADULTS.

Depression and anxiety

Beristianos MH, Maguen S, Neylan TC, Byers AL

Trauma Exposure and Risk of Suicidal Ideation Among Older Adults.

American Journal of Geriatric Psychiatry

Beristianos MH, Maguen S, Neylan TC, Byers AL

Mental Health Service Use Across the Life Course Among Adults With Psychiatric Disorders and Prior Suicidal Behavior.

Psychiatric services (Washington, D.C.)

Byers AL, Lai AX, Arean P, Nelson JC, Yaffe K

Leisure activities and depressive symptoms in older adults with cognitive complaints.

International psychogeriatrics

Poelke G, Ventura MI, Byers AL, Yaffe K, Sudore R, Barnes DE

Sleep Quality and Risk of Dementia Among Older Male Veterans.

American Journal of Geriatric Psychiatry

Yaffe K, Nettiksimmons J, Yesavage J, Byers A

PTSD and Risk of Incident Cardiovascular Disease in Aging Veterans.

American Journal of Geriatric Psychiatry

Beristianos MH, Yaffe K, Cohen B, Byers AL

Traumatic brain injury and risk of dementia in older veterans.

Neurology

Barnes DE, Kaup A, Kirby KA, Byers AL, Diaz-Arrastia R, Yaffe K

Depression and dementias among military veterans.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Byers AL, Yaffe K

Lifestyle and health-related risk factors and risk of cognitive aging among older veterans.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Yaffe K, Hoang TD, Byers AL, Barnes DE, Friedl KE

Prisoner of war status, posttraumatic stress disorder, and dementia in older veterans.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Meziab O, Kirby KA, Williams B, Yaffe K, Byers AL, Barnes DE

Chronicity of posttraumatic stress disorder and risk of disability in older persons.

JAMA psychiatry

Byers AL, Covinsky KE, Neylan TC, Yaffe K

Alcohol consumption patterns and cognitive impairment in older women.

American Journal of Geriatric Psychiatry

Hoang TD, Byers AL, Barnes DE, Yaffe K

Cognitive outcomes after psychotherapeutic interventions for major depression in older adults with executive dysfunction.

American Journal of Geriatric Psychiatry

Mackin RS, Nelson JC, Delucchi K, Raue P, Byers A, Barnes D, Satre DD, Yaffe K, Alexopoulos GS, Arean PA

Long-term cumulative depressive symptom burden and risk of cognitive decline and dementia among very old women.

The journals of gerontology. Series A, Biological sciences and medical sciences

Zeki Al Hazzouri A, Vittinghoff E, Byers A, Covinsky K, Blazer D, Diem S, Ensrud KE, Yaffe K

Twenty-year depressive trajectories among older women.

Archives of general psychiatry

Byers AL, Vittinghoff E, Lui LY, Hoang T, Blazer DG, Covinsky KE, Ensrud KE, Cauley JA, Hillier TA, Fredman L, Yaffe K

Dysthymia and depression increase risk of dementia and mortality among older veterans.

American Journal of Geriatric Psychiatry

Byers AL, Covinsky KE, Barnes DE, Yaffe K

Midlife vs late-life depressive symptoms and risk of dementia: differential effects for Alzheimer disease and vascular dementia.

Archives of general psychiatry

Barnes DE, Yaffe K, Byers AL, McCormick M, Schaefer C, Whitmer RA

Low use of mental health services among older Americans with mood and anxiety disorders.

Psychiatric services (Washington, D.C.)

Byers AL, Arean PA, Yaffe K

Depression and risk of developing dementia.

Nature reviews. Neurology

Byers AL, Yaffe K

High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey Replication.

Archives of general psychiatry

Byers AL, Yaffe K, Covinsky KE, Friedman MB, Bruce ML

Heritability of depressive symptoms: a case study using a multilevel approach.

International journal of methods in psychiatric research

Byers AL, Levy BR, Kasl SV, Bruce ML, Allore HG

Depression and risk for adverse falls in older home health care patients.

Research in gerontological nursing

Byers AL, Sheeran T, Mlodzianowski AE, Meyers BS, Nassisi P, Bruce ML

When parents matter to their adult children: filial reliance associated with parents' depressive symptoms.

The journals of gerontology. Series B, Psychological sciences and social sciences

Byers AL, Levy BR, Allore HG, Bruce ML, Kasl SV

Range and severity of symptoms over time among older adults with chronic obstructive pulmonary disease and heart failure.

Archives of internal medicine

Walke LM, Byers AL, Tinetti ME, Dubin JA, McCorkle R, Fried TR

A randomized trial of depression assessment intervention in home health care.

Journal of the American Geriatrics Society

Bruce ML, Brown EL, Raue PJ, Mlodzianowski AE, Meyers BS, Leon AC, Heo M, Byers AL, Greenberg RL, Rinder S, Katt W, Nassisi P

Changes in preferences for life-sustaining treatment among older persons with advanced illness.

Journal of general internal medicine

Fried TR, Van Ness PH, Byers AL, Towle VR, O'Leary JR, Dubin JA

The association of symptoms with health outcomes in chronically ill adults.

Journal of pain and symptom management

Walke LM, Byers AL, Gallo WT, Endrass J, Fried TR

Prospective study of health status preferences and changes in preferences over time in older adults.

Archives of internal medicine

Fried TR, Byers AL, Gallo WT, Van Ness PH, Towle VR, O'Leary JR, Dubin JA

Symptom assessment in community-dwelling older adults with advanced chronic disease.

Journal of pain and symptom management

Walke LM, Byers AL, McCorkle R, Fried TR

Unmet desire for caregiver-patient communication and increased caregiver burden.

Journal of the American Geriatrics Society

Fried TR, Bradley EH, O'Leary JR, Byers AL

Application of negative binomial modeling for discrete outcomes: a case study in aging research.

Journal of clinical epidemiology

Byers AL, Allore H, Gill TM, Peduzzi PN

A program to prevent functional decline in physically frail, elderly persons who live at home.

The New England journal of medicine

Gill TM, Baker DI, Gottschalk M, Peduzzi PN, Allore H, Byers A